Mouse anti-CBL Monoclonal Antibody, clone XB-a12, det
Cat No | BXXB-184 |
Conjugate | |
Type | 抗體對(duì) |
Clone | XB-a12 |
Source | Mouse |
Size | 1 mg |
Application | GICA |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Store at -20 degree for long time. Avoid repeated freeze/thaw cycles. |
Synonyms | C CBL;Cas Br M (murine) ecotropic retroviral transforming sequence;Casitas B lineage lymphoma proto oncogene;Casitas B-lineage lymphoma proto-oncogene;cbl;CBL 2;CBL_HUMAN;CBL2;E3 ubiquitin protein ligase CBL;E3 ubiquitin-protein ligase CBL;Oncogene CBL2;Proto oncogene c CBL;Proto-oncogene c-CBL;RGD1561386;RING finger protein 55;RNF55;Signal transduction protein CBL |
Purification | Protein A |
MolecularWeight | |
Description | |
Background | Participates in signal transduction in hematopoietic cells. Adapter protein that functions as a negative regulator of many signaling pathways that start from receptors at the cell surface. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Recognizes activated receptor tyrosine kinases, including PDGFA, EGF and CSF1, and terminates signaling. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.