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Rabbit Anti-GSPT1 Polyclonal Antibody

Cat NoBIOS-1065P
Conjugate
Type多克隆抗体
SourceRabbit
Size1mg
ApplicationWB
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in 0.01 M PBS; pH 7.4.
StorageStore at -20 degree for long term.
SynonymsGSPT1;551G9.2;ETF3A;GST1;eRF3a
PurificationAffinity purification
MolecularWeight80KDa
Description
BackgroundeRF3a (eukaryotic peptide chain release factor subunit 3a); also known as GSPT1 (G1 to S phase transition 1); is a 499 amino acid protein that belongs to the GTP-binding elongation factor family and is involved in the regulation of cell growth; specifically via control of translation termination. Human eRF3a shares 94% sequence identity with its mouse counterpart; suggesting a conserved function between species. The gene encoding eRF3a maps to human chromosome 16; which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and; with mutation; may lead to giant axonal neuropathy; a nervous system disorder characterized by increasing malfunction with growth.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.
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