Rabbit Anti-RGS14 Polyclonal Antibody
Cat No | BIOS-1095P |
Conjugate | |
Type | 多克隆抗體 |
Source | Rabbit |
Size | 1mg |
Application | WB; IHC |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in 0.01 M PBS; pH 7.4. |
Storage | Store at -20 degree for long term. |
Synonyms | RGS14;Regulator of G-protein signaling 14 |
Purification | Affinity purification |
MolecularWeight | 54KDa |
Description | |
Background | This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain; two Raf-like Ras-binding domains (RBDs); and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding; through its GoLoco domain; to specific types of activated; GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP); the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers; forming inactive G-protein heterotrimers; thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.