Background | Carboxyl Dextrans (Dextran-COOH) is a premier reactive dextran conjugate that can be used to react with other chemical groups. Carboxylic functional dextrans can react with amino groups in aqueous solution. These functional dextrans were purified by size-exclusion chromatography to remove non-conjugated molecules and ensure adequate applications both in-vitro and in-vivo. Dextrans are naturally synthesized polysaccharides with good water solubility, low toxicity and varied molecular weights. Dextrans modified with dyes and other iomolecules have been successfully used as long-term tracers for live cells. |