Cat No | BIOMY106-A |
Conjugate | |
Type | 其他重組蛋白 |
Source | HEK293 |
Tag | His |
Size | 100 ug |
Application | |
Format | Lyophilized |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS |
Species | Human |
Storage | Store at –20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | hepatitis A virus cellular receptor 1;CD365;HACVR;HAVCR;HAVCR-1;KIM-1;KIM1;TIM;TIM-1;TIM1;TIMD-1;TIMD1;TIM-1/KIM-1 |
Purification | > 90 % as determined by SDS-PAGE |
MolecularWeight | 31.3 kDa |
Description | |
Background | HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulin mucin 1 (TIM-1), is a type of integral membrane glycoprotein. KIM-1 protein is widely expressed with the highest levels in the kidney and testis. It has been shown to play a major role as a human susceptibility gene for asthma, allergy, and autoimmunity. IgA1lambda is a specific ligand of KIM-1 protein and that their association has a synergistic effect in virus-receptor interactions. KIM-1 involves in the pathogenesis of acute kidney injury. It had been confirmed that KIM-1 is a human urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novel regulatory molecule of flow-induced calcium signaling. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.