Recombinant Human TL1A/TNFSF15 Protein(aa 72-251)
Cat No | BIOP2209 |
Conjugate | |
Type | 免疫檢查點(diǎn) |
Source | E. coli |
Size | 10 ug |
Application | Immunogen |
Format | Lyophilized |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in 20mM Tris, 50mM NaCl, 5% glycerol, pH 8.0. |
Species | Human |
Storage | Store at –20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | TL1;TL1A;TNLG1B;VEGI;VEGI192A |
Purification | > 90% by SDS-PAGE. |
MolecularWeight | |
Description | aa 72-251 |
Background | The protein is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.