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Cat No | BQSB-1003 |
Conjugate | |
Type | 重组兔单抗 |
Clone | BT2947 |
Source | Rabbit |
Tag | N/A |
Size | 1 mg |
Application | WB |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Synonyms | 白细胞介素-7受体a;IL-7Rα;IL-7Ra;Interleukin-7 receptor subunit alpha;CD 127;CD127;CD127 antigen;CDW127;IL 7R alpha;IL 7R;IL-7 receptor subunit alpha;IL-7R subunit alpha;IL-7R-alpha;IL7RA;IL7Ralpha;Interleukin 7 receptor alpha chain;Interleukin 7 receptor;Interleukin 7 receptor isoform H5 6;IL7RA_HUMAN |
Purification | |
MolecularWeight | |
Description | |
Background | The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). |