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Recombinant Rabbit Anti-beta Arrestin 1 Monoclonal Antibody, clone BT3018

Cat NoBQSB-1074
Conjugate
Type重组兔单抗
CloneBT3018
SourceRabbit
TagN/A
Size1 mg
ApplicationWB; IHC-P; IHC-F; ICC/IF; IF; Flow-Cyt
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS.
StorageShipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Synonymsβ-抑制蛋白1;ARRB1;ARB1;ARR1;Arrestin beta 1;Beta arrestin 1
Purification
MolecularWeight
Description
BackgroundFunctions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta-arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC; Biotin; Alexa Fluor; Rhodamine B; Cy; Co-Au.
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