Recombinant Rabbit Anti-INPP4B Monoclonal Antibody, clone BT3126
Cat No | BQSB-1182 |
Conjugate | |
Type | 重組兔單抗 |
Clone | BT3126 |
Source | Rabbit |
Tag | N/A |
Size | 1 mg |
Application | WB; IHC-P; IHC-F; Flow-Cyt; IF |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Synonyms | 聚磷酸肌醇磷酸酶4B;4-bisphosphate 4-phosphatase;Inositol polyphosphate 4 phosphatase type II 105kDa;Inositol polyphosphate 4-phosphatase type II;Inpp4b;MGC132014;Type II inositol 3,4 bisphosphate 4 phosphatase;Type II inositol-3 |
Purification | |
MolecularWeight | |
Description | |
Background | Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate and inositol 3,4-trisphosphate. Plays a role in the late stages of macropinocytosis by dephosphorylating phosphatidylinositol 3,4-bisphosphate in membrane ruffles.The lipid phosphatase activity is critical for tumor suppressor function. Antagonizes the PI3K-AKT/PKB signaling pathway by dephosphorylating phosphoinositides and thereby modulating cell cycle progression and cell survival. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC; Biotin; Alexa Fluor; Rhodamine B; Cy; Co-Au.