Recombinant Rabbit Anti-Cyclin H Monoclonal Antibody, clone BT3268
Cat No | BQSB-1324 |
Conjugate | |
Type | 重組兔單抗 |
Clone | BT3268 |
Source | Rabbit |
Tag | N/A |
Size | 1 mg |
Application | WB; IHC-P; IHC-F; ICC/IF; IF; IP; Flow-Cyt |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Synonyms | 周期素H;CAK;CCNH;CDK-activating kinase;cyclin H;cyclin-dependent kinase-activating kinase;Cyclin-H;MO15-associated protein;p34;p37 |
Purification | |
MolecularWeight | |
Description | |
Background | Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC; Biotin; Alexa Fluor; Rhodamine B; Cy; Co-Au.