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Cat No | BQSB-1373 |
Conjugate | |
Type | 重组兔单抗 |
Clone | BT3317 |
Source | Rabbit |
Tag | N/A |
Size | 1 mg |
Application | WB; IP; Flow-Cyt |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Synonyms | 死亡受体5;Death receptor 5;TRAIL receptor 2;TRAIL-R2;CD262;TNFRSF10B;DR5;KILLER;TRAILR2;TRICK2;ZTNFR9 |
Purification | |
MolecularWeight | |
Description | |
Background | Receptor for the cytotoxic ligand TNFSF10/TRAIL.The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. |