Recombinant Rabbit Anti-MBD1 Monoclonal Antibody, clone BT3359
Cat No | BQSB-1415 |
Conjugate | |
Type | 重組兔單抗 |
Clone | BT3359 |
Source | Rabbit |
Tag | N/A |
Size | 1 mg |
Application | WB; IHC-P; IHC-F; ICC/IF; IF; IP |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Synonyms | 甲基化CpG結(jié)合蛋白;CXXC 3;Mbd1;MECP1 COMPLEX;PCM1;RFT |
Purification | |
MolecularWeight | |
Description | |
Background | Transcriptional repressor that binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binding is abolished by the presence of 7-mG that is produced by DNA damage by methylmethanesulfonate (MMS). Acts as transcriptional repressor and plays a role in gene silencing by recruiting ATF7IP, which in turn recruits factors such as the histone methyltransferase SETDB1. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC; Biotin; Alexa Fluor; Rhodamine B; Cy; Co-Au.