Recombinant Rabbit Anti-SIN3A Monoclonal Antibody, clone BT3399
Cat No | BQSB-1455 |
Conjugate | |
Type | 重組兔單抗 |
Clone | BT3399 |
Source | Rabbit |
Tag | N/A |
Size | 1 mg |
Application | WB; IHC-P; IHC-F; ICC/IF; IF; Flow-Cyt |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Synonyms | 同源轉(zhuǎn)錄調(diào)節(jié)蛋白Sin3A;Histone deacetylase complex subunit Sin 3a;Paired amphipathic helix protein Sin 3a;SIN3 homolog A |
Purification | |
MolecularWeight | |
Description | |
Background | Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in the control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC; Biotin; Alexa Fluor; Rhodamine B; Cy; Co-Au.