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Cat No | BQSB-148 |
Conjugate | |
Type | 重组兔单抗 |
Clone | BT2100 |
Source | Rabbit |
Tag | N/A |
Size | 1 mg |
Application | WB; IHC-P; IHC-F; ICC/IF; IF |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Synonyms | 相关死亡促进因子Bad;Mitogen-Activated Protein Kinase 1;Extracellular Signal-Regulated Kinase 2;Mitogen-Activated Protein Kinase 2;MAP Kinase Isoform P42;MAP Kinase 1;MAP Kinase 2;EC 2.7.11.24;P42-MAPK;MAPK 2;PRKM1;PRKM2;ERK-2;ERK2;ERT1;Protein Tyrosine Kinase ERK2;EC 2.7.11;P42MAPK;P41mapk;MAPK 1;MAPK2;P38;P40;ERK |
Purification | |
MolecularWeight | |
Description | |
Background | Bad is a member of the Bcl2 family and acts to promote apoptosis by forming heterodimers with the survival proteins Bcl2 and BclxL, thus preventing them from binding with BAX. Bad is found on the outer mitochondrial membrane and, once phosphorylated in response to growth stimuli, translocates to the cytoplasm. The phosphorylation status of Bad represents a key checkpoint for death or cell survival. |