Recombinant Rabbit Anti-MELK Monoclonal Antibody, clone BT3529
Cat No | BQSB-1585 |
Conjugate | |
Type | 重組兔單抗 |
Clone | BT3529 |
Source | Rabbit |
Tag | N/A |
Size | 1 mg |
Application | WB |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Synonyms | 蛋白激酶MPK38;hMELK;hPK38;MELK;mKIAA0175;MPK38 |
Purification | |
MolecularWeight | |
Description | |
Background | Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation. Has a broad substrate specificity; phosphorylates BCL2L14, CDC25B, MAP3K5/ASK1 and ZNF622. Acts as an activator of apoptosis by phosphorylating and activating MAP3K5/ASK1. Acts as a regulator of cell cycle, notably by mediating phosphorylation of CDC25B, promoting localization of CDC25B to the centrosome and the spindle poles during mitosis. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC; Biotin; Alexa Fluor; Rhodamine B; Cy; Co-Au.