Recombinant Rabbit Anti-DKK3 Monoclonal Antibody, clone BT3889
Cat No | BQSB-1945 |
Conjugate | |
Type | 重組兔單抗 |
Clone | BT3889 |
Source | Rabbit |
Tag | N/A |
Size | 1 mg |
Application | WB; ICC/IF; IP |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Synonyms | 抑癌蛋白DKK3;RIG;REIC |
Purification | |
MolecularWeight | |
Description | |
Background | Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC; Biotin; Alexa Fluor; Rhodamine B; Cy; Co-Au.