Recombinant Rabbit Anti-ERCC8 Monoclonal Antibody, clone BT4212
Cat No | BQSB-2268 |
Conjugate | |
Type | 重組兔單抗 |
Clone | BT4212 |
Source | Rabbit |
Tag | N/A |
Size | 1 mg |
Application | WB; IP |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Synonyms | 科凱恩氏綜合癥相關(guān)蛋白/早衰蛋白CSA;CKN1;CSA;ERCC8 |
Purification | |
MolecularWeight | |
Description | |
Background | Substrate-recognition component of the CSA complex, a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex, involved in transcription-coupled nucleotide excision repair. The CSA complex (DCX(ERCC8) complex) promotes the ubiquitination and subsequent proteasomal degradation of ERCC6 in a UV-dependent manner; ERCC6 degradation is essential for the recovery of RNA synthesis after transcription-coupled repair. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC; Biotin; Alexa Fluor; Rhodamine B; Cy; Co-Au.