Recombinant Rabbit Anti-RGMA Monoclonal Antibody, clone BT4300
Cat No | BQSB-2356 |
Conjugate | |
Type | 重組兔單抗 |
Clone | BT4300 |
Source | Rabbit |
Tag | N/A |
Size | 1 mg |
Application | WB; ICC/IF |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Synonyms | 反義導(dǎo)向分子RGMA;Repulsive guidance molecule A;RGM;RGM domain family member A;RGMA |
Purification | |
MolecularWeight | |
Description | |
Background | Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system. Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses. Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG-PTK2/FAK1 cascade, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC; Biotin; Alexa Fluor; Rhodamine B; Cy; Co-Au.