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Cat No | BQSB-2435 |
Conjugate | |
Type | 重组兔单抗 |
Clone | BT4379 |
Source | Rabbit |
Tag | N/A |
Size | 1 mg |
Application | WB; ICC/IF; IP; Flow-Cyt |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Synonyms | ABRA1;ABRAXAS;FAM175A |
Purification | |
MolecularWeight | |
Description | |
Background | Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. |