Recombinant Rabbit Anti-GRK6 Monoclonal Antibody, clone BT4406
Cat No | BQSB-2462 |
Conjugate | |
Type | 重組兔單抗 |
Clone | BT4406 |
Source | Rabbit |
Tag | N/A |
Size | 1 mg |
Application | WB |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Synonyms | G蛋白偶聯(lián)受體激酶6;G protein coupled receptor kinase 6;G protein coupled receptor kinase GRK6;G protein-coupled receptor kinase 6;Gprk6;Grk6 |
Purification | |
MolecularWeight | |
Description | |
Background | Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis.Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro). |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC; Biotin; Alexa Fluor; Rhodamine B; Cy; Co-Au.