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Recombinant Rabbit Anti-GRK6 Monoclonal Antibody, clone BT4406

Cat NoBQSB-2462
Conjugate
Type重组兔单抗
CloneBT4406
SourceRabbit
TagN/A
Size1 mg
ApplicationWB
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS.
StorageShipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
SynonymsG蛋白偶联受体激酶6;G protein coupled receptor kinase 6;G protein coupled receptor kinase GRK6;G protein-coupled receptor kinase 6;Gprk6;Grk6
Purification
MolecularWeight
Description
BackgroundSpecifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis.Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro).
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC; Biotin; Alexa Fluor; Rhodamine B; Cy; Co-Au.
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