Recombinant Rabbit Anti-BLNK Monoclonal Antibody, clone BT4427
Cat No | BQSB-2483 |
Conjugate | |
Type | 重組兔單抗 |
Clone | BT4427 |
Source | Rabbit |
Tag | N/A |
Size | 1 mg |
Application | WB; IHC-P; IHC-F; IF |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Synonyms | B淋巴細(xì)胞連接蛋白;AGM4;BASH;Bca;BLNK;Ly57;Lyw57;SLP65 |
Purification | |
MolecularWeight | |
Description | |
Background | Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca2+ mobilization and is required for trafficking of the BCR to late endosomes. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC; Biotin; Alexa Fluor; Rhodamine B; Cy; Co-Au.