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Cat No | BQSB-2584 |
Conjugate | |
Type | 重组兔单抗 |
Clone | BT4528 |
Source | Rabbit |
Tag | N/A |
Size | 1 mg |
Application | WB; ICC/IF; Flow-Cyt |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Synonyms | 泛素融合降解样蛋白1;UB fusion protein 1;UFD1;UFD1L |
Purification | |
MolecularWeight | |
Description | |
Background | Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. |