Recombinant Rabbit Anti-TRIM28 Monoclonal Antibody, clone BT4819
Cat No | BQSB-2875 |
Conjugate | |
Type | 重組兔單抗 |
Clone | BT4819 |
Source | Rabbit |
Tag | N/A |
Size | 1 mg |
Application | WB; IHC-P; IHC-F; ICC/IF; IF; Flow-Cyt |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Synonyms | 轉(zhuǎn)錄中介因子Tif1β;E3 SUMO-protein ligase TRIM28;KRAB-associated protein 1;KAP-1;KRAB-interacting protein 1;KRIP-1;Nuclear corepressor KAP-1;KAP1;TF1B;RNF96;TIF1B;TRIM28 |
Purification | |
MolecularWeight | |
Description | |
Background | Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC; Biotin; Alexa Fluor; Rhodamine B; Cy; Co-Au.