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Recombinant Rabbit Anti-ABCG2 Monoclonal Antibody, clone BT2535

Cat NoBQSB-587
Conjugate
Type重组兔单抗
CloneBT2535
SourceRabbit
TagN/A
Size1 mg
ApplicationWB,IHC-P,IHC-F,ICC/IF,IF
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS.
StorageShipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Synonyms三磷酸腺苷结合转运蛋白G超家族成员2;100 kDa NT receptor;Glycoprotein 95;Gp 95;Gp95;Neurotensin receptor 3;NT 3;NT3;NTR 3;NTR3;SORT 1;SORT_HUMAN;SORT1 (gene name);SORT1;Sortilin 1;Sortilin;Sortilin1
Purification
MolecularWeight
Description
BackgroundAn ABC transporter. Allows efflux of Hoechst dye, a property that has been used to separate bone marrow side population cells, which express BCRP/ABCG2. Appears to play a major role in the multidrug resistance phenotype of a specific MCF-7 breast cancer cell line. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC; Biotin; Alexa Fluor; Rhodamine B; Cy; Co-Au.
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