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Cat No | BQSB-624 |
Conjugate | |
Type | 重组兔单抗 |
Clone | BT2572 |
Source | Rabbit |
Tag | N/A |
Size | 1 mg |
Application | WB,IHC-P,ICC/IF,IF,IHC-F |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Synonyms | α横纹肌辅肌动蛋白;TMIG1_HUMAN;TMIGD-1;Transmembrane and immunoglobulin domain-containing protein 1 |
Purification | |
MolecularWeight | |
Description | |
Background | Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. |