Recombinant Rabbit Anti-TXNIP Monoclonal Antibody, clone BT2611
Cat No | BQSB-663 |
Conjugate | |
Type | 重組兔單抗 |
Clone | BT2611 |
Source | Rabbit |
Tag | N/A |
Size | 1 mg |
Application | WB |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Synonyms | 硫氧還蛋白結(jié)合蛋白2;MLH1_HUMAN;DNA mismatch repair protein Mlh1;COCA2;MutL protein homolog 1;FCC2;HNPCC;MLH-1;hMLH1;HNPCC2 |
Purification | |
MolecularWeight | |
Description | |
Background | TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. It interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC; Biotin; Alexa Fluor; Rhodamine B; Cy; Co-Au.