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Recombinant Rabbit Anti-IL-15 Monoclonal Antibody, clone BT2677, det

Cat NoBQSB-728-D
Conjugate
Type抗体对
CloneBT2677
SourceRabbit
TagN/A
Size1 mg
ApplicationELISA
ApplicationNoteRecommended Antibody pairs: BQSB-728-C-BQSB-728-D
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS.
StorageShipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
SynonymsInterleukin-15;IL-15
Purification
MolecularWeight
Description
BackgroundThe protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC; Biotin; Alexa Fluor; Rhodamine B; Cy; Co-Au.
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