Recombinant Rabbit Anti-UPK3A Monoclonal Antibody, clone BT2902
Cat No | BQSB-958 |
Conjugate | |
Type | 重組兔單抗 |
Clone | BT2902 |
Source | Rabbit |
Tag | N/A |
Size | 1 mg |
Application | IHC-P; IHC-F; IF |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Synonyms | 尿路上皮特異蛋白3;Cytokine Zcyto10;Four alpha helix cytokine;IL-20;IL10D;IL20;IL20_HUMAN;Interleukin 20;Interleukin-20;MGC96907;UNQ852/PRO1801 |
Purification | |
MolecularWeight | |
Description | |
Background | The asymmetric unit membrane (AUM) forms numerous plaques, which cover the apical surface of the urothelium. These plaques are thought to strengthen the urothelium and reduce the risk of rupturing during ladder distention. They are composed of four major integral membrane proteins called uroplakins (UP). The uroplakin family comprises UPIa, UPIb, UPII, and UPIII. Family members are conserved among several species, including human, mouse, rat, rabbit, dog, pig and sheep. UPIa and UPIb form tightly packed structures with UPII and UPIII, respectively. This pairing is required for normal urothelial plaque formation and is regulated by proteolytic processing of the uroplakin proteins. Uroplakins are expressed in normal urothelium and are used as specific markers of urothelial differentiation. They are also expressed in a majority of transitional cell carcinomas of the bladder (TCCs), which make the uroplakins a useful marker for detecting bladder cancer metastasis and for staging and monitoring chemotherapeutic response. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC; Biotin; Alexa Fluor; Rhodamine B; Cy; Co-Au.