Recombinant Rabbit Anti-CSK Monoclonal Antibody, clone BT2909
Cat No | BQSB-965 |
Conjugate | |
Type | 重組兔單抗 |
Clone | BT2909 |
Source | Rabbit |
Tag | N/A |
Size | 1 mg |
Application | WB |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Synonyms | 酪氨酸激酶C-SRC;AI098070;aPKCzeta;C80388;EC 2.7.11.13;KPCZ_HUMAN;nPKC zeta;nPKC-zeta;OTTHUMP00000001368;OTTHUMP00000044160;PKC 2;PKC ZETA;PKC2;Pkcz;PKCZETA;PKM-zeta, included;PRKCZ;Protein kinase C zeta;Protein kinase C zeta form |
Purification | |
MolecularWeight | |
Description | |
Background | All members of the Src gene family of tyrosine kinases are characterized by a carboxy terminal domain tyrosine which is highly phosphorylated in the inactive form of the enzyme and phosphorylated to a much lesser extent when the enzyme is active. In the case of Src p60, Y527 is this tyrosine; however, a mutant form of c-Src in which Y527 is replaced by phenylalanine is transforming and displays 5- to 10-fold elevated kinase activity compared to its normal counterpart. Csk has been identified as a Src-related tyrosine kinase having both SH2 and SH3 domains and a catalytic domain but lacking sequences amino terminal to the SH3 domain as well as carboxy terminal regulatory sequences. Csk phosphorylates Src on Y527 and also downregulates Lyn, Fyn and Lck by tyrosine phosphorylation of carboxy terminal regulatory sites. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC; Biotin; Alexa Fluor; Rhodamine B; Cy; Co-Au.