Recombinant Rabbit Anti-IRAK Monoclonal Antibody, clone BT2928
Cat No | BQSB-984 |
Conjugate | |
Type | 重組兔單抗 |
Clone | BT2928 |
Source | Rabbit |
Tag | N/A |
Size | 1 mg |
Application | WB |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
Synonyms | 白介素-1受體相關(guān)激酶1;Krt14;KRT14;CK14;EBS3;EBS4;K14;NFJ;keratin 14 |
Purification | |
MolecularWeight | |
Description | |
Background | Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Isoform 1 binds rapidly but is then degraded allowing isoform 2 to mediate a slower, more sustained response to the cytokine. Isoform 2 is inactive suggesting that the kinase activity of this enzyme is not required for IL-1 signaling. Once phosphorylated, IRAK1 recruits the adapter protein PELI1. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC; Biotin; Alexa Fluor; Rhodamine B; Cy; Co-Au.