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  - --|--|重組兔單抗
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  - --|--|小分子抗原抗體
  - --|--|抗體對
  - --|--|標簽抗體
  - --|--|修飾性抗體
  - --|--|其他抗體
- 二抗
- 試劑盒
  - --|--|標記試劑盒
  - --|--|其他試劑盒
  - --|--|ELISA試劑盒
  - --|--|標記染料
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  - --|--|金納米球
  - --|--|金納米棒
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  - --|--|碳納米顆粒
  - --|--|特殊納米顆粒
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  - --|--|橙色熒光微球
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  - --|--|Magnetic Particles Conjugates
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  - --|--|PET微球/聚對苯二甲酸乙二醇酯-模版法
  - --|--|PVA微球/聚乙烯醇-模版法
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  - --|--|PLLA微球/聚左旋乳酸-100%純度
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  - --|--|PTFE微球/聚四氟乙烯-100%純度
  - --|--|PBS微球聚丁二酸丁二醇酯-100%純度
  - --|--|Polydopamine微球聚多巴胺-100%純度
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  - --|--|Sodium Alginate微球/海藻酸鈉
  - --|--|Agarose微球/瓊脂糖
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  - --|--|藍色染色微球
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  - --|--|上轉換納米顆粒
  - --|--|量子點
  - --|--|色譜填料
  - --|--|纖維素微球
  - --|--|介孔材料
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  - --|--|轉染試劑
  - --|--|ELISA-FCM試劑
  - --|--|WB試劑
  - --|--|IHC-ICC-IF試劑
  - --|--|載體材料

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Rabbit Anti-Acetyl-Histone H3 (Lys4) Polyclonal Antibody

Description
Documentation
Citations

Cat No	BSPA-0528
Conjugate
Type	Polyclonal Antibody
Source	Rabbit
Size	1 mg
Application	WB; ICC/IF
Format	Liquid
Concentration	Please refer to the vial lable for the specific concentration.
Buffer	Supplied in PBS.
Storage	Store at -20 degree. Avoid repeted freeze/thaw cycl.
Synonyms	H3 histone family, member A;H3/A;H31;H3FA;H3FB;H3FC;H3FD;H3FF;H3FH;H3FI;H3FJ;H3FK;H3FL;HIST1H3A;HIST1H3B;HIST1H3C;HIST1H3D;HIST1H3E
Purification
Note	Tis product l is eeze eezeleezeegrrch useeze ly, no useeze huma, apeut agnost apcal.
MolecularWeight
Description
Background	The nucleosome, made up of four core histone proteins (H2A, H2B, H3, and H4), is the primary building block of chromatin. Originally thought to function as a static scaffold for DNA packaging, histones have now been shown to be dynamic proteins, undergoing multiple types of post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination. Histone acetylation occurs mainly on the amino-terminal tail domains of histones H2A (Lys5), H2B (Lys5, 12, 15, and 20), H3 (Lys9, 14, 18, 23, 27, 36, and 56), and H4 (Lys5, 8, 12, and 16) and is important for the regulation of histone deposition, transcriptional activation, DNA replication, recombination, and DNA repair. Hyper-acetylation of the histone tails neutralizes the positive charge of these domains and is believed to weaken histone-DNA and nucleosome-nucleosome interactions, thereby destabilizing chromatin structure and increasing the accessibility of DNA to various DNA-binding proteins. In addition, acetylation of specific lysine residues creates docking sites for a protein module called the bromodomain, which binds to acetylated lysine residues. Many transcription and chromatin regulatory proteins contain bromodomains and may be recruited to gene promoters, in part, through binding of acetylated histone tails. Histone acetylation is mediated by histone acetyltransferases (HATs), such as CBP/p300, GCN5L2, PCAF, and Tip60, which are recruited to genes by DNA-bound protein factors to facilitate transcriptional activation. Deacetylation, which is mediated by histone deacetylases (HDAC and sirtuin proteins), reverses the effects of acetylation and generally facilitates transcriptional repression.

We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.

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Rabbit Anti-Acetyl-Histone H3 (Lys4) Polyclonal Antibody